Parinaud’s oculoglandular syndrome secondary to sporotricosis
case report
DOI:
https://doi.org/10.29352/mill0217.24636Keywords:
sporotrichosis, parinaud’s oculoglandular syndrome, granulomatous conjunctivitisAbstract
Introduction: Parinaud's Oculoglandular Syndrome is a rare granulomatous conjunctivitis, accompanied by regional lymphadenopathy. It is caused by varied etiologies, one of which is sporotrichosis, which is a rare cause and little reported in the literature.
Objective: To report a case of Parinaud's Oculoglandular Syndrome caused by atypical sporotrichosis, associated with dacryocystitis, attended by an emergency eye service.
Methods: The study was carried out from the analysis of the medical record, along with the anamnesis, ophthalmological examination and complementary examinations of the patient. Bibliographic research was carried out with publications of up to twenty years for theoretical and methodological foundations.
Results: It was possible to identify some of the most common changes in Parinaud's Oculoglandular Syndrome due to sporotrichosis. Such changes consist of hyperemic nodules in the tarsal or bulbar conjunctiva, related with adenopathy, hardened or fibroelastic, in submandibular and / or preauricular regions.
Conclusion: Sporotrichosis is a disease with an effective treatment if readily identified and should always be considered as a possible cause of Parinaud's Oculoglandular Syndrome. This case can be a reference for professionals in the field, both in diagnosis and in the management of patients with such syndromic diagnosis, since it is a rare and rarely seen case.
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References
Azari, A. A., & Barney, N. P. (2013). Conjunctivitis: a systematic review of diagnosis and treatment. JAMA, 310(16), 1721–1729. https://doi.org/10.1001/jama.2013.280318
Barros, M. B. D. L., Schubach, A. D. O., do Valle, A. C. F., Galhardo, M. C. G., Conceição-Silva, F., Schubach, T. M. P.,... Conceiçao, M. J. (2004). Cat-transmitted sporotrichosis epidemic in Rio de Janeiro, Brazil: description of a series of cases. Clinical Infectious Diseases, 38(4), 529-535. DOI: 10.1086/381200
Biancardi, A. L., Medling, L., Cravo, D. S., Perrota, R., Anjo, P., Vieira, H., & Junior, D. M. (2019). Esporotricose ocular: manifestações atípicas. 78(1), 59–61. https://doi.org/10.5935/0034-7280.201
Bonifaz, A., & Tirado-Sánchez, A. (2017). Cutaneous disseminated and extracutaneous sporotrichosis: current status of a complex disease. Journal of Fungi, 3(1), 6. DOI: 10.3390/jof3010006
Chakrabarti, A., Bonifaz, A., Gutierrez-Galhardo, M. C., Mochizuki, T., & Li, S. (2014). Global epidemiology of sporotrichosis. Medical Mycology, 53(1), 3–14. https://doi.org/10.1093/mmy/myu062
Chakrabarti, A., Bonifaz, A., Gutierrez-Galhardo, M. C., Mochizuki, T., & Li, S. (2015). Global epidemiology of sporotrichosis. Medical mycology, 53(1), 3-14. DOI: 10.1093/mmy/myu062
da Silva, M. B. T., de Mattos Costa, M. M., da Silva Torres, C. C., Gutierrez Galhardo, M. C., do Valle, A. C. F., Magalhães, M. de A. F. M., Sabroza, P. C., & de Oliveira, R. M. (2012). Esporotricose urbana: Epidemia negligenciada no Rio de Janeiro, Brasil. Cadernos de Saude Publica, 28(10), 1867–1880. https://doi.org/10.1590/S0102-311X2012001000006
de Abreu Ribeiro, A. S., Bisol, T., & Ana Menezes, M. S. (2010). Síndrome oculoglandular de Parinaud causada por esporotricose. Revista Brasileira de Oftalmologia, 69(5), 317–322. https://doi.org/10.1590/S0034-72802010000500008
Ferreira, C. P., Nery, J. A. da C., de Almeida, A. C. O., Ferreira, L. C., Corte-Real, S., & Conceição-Silva, F. (2014). Parinaud’s oculoglandular syndrome associated with Sporothrix schenckii. IDCases, 1(3), 38–39. https://doi.org/10.1016/j.idcr.2014.05.001
Kauffman, C. A., Bustamante, B., Chapman, S. W., & Pappas, P. G. (2007). Clinical practice guidelines for the management of sporotrichosis: 2007 update by the Infectious Diseases Society of America. Clinical Infectious Diseases, 45(10), 1255-1265. https://doi.org/10.1086/522765
Madureira, L. da S., Gatti, R. F., Prohmann, C. M., Sanmiguel, J., De Almeida, M. T. G., Mattar, F. R. de O., & Antonio, J. R. (2018). Síndrome Oculoglandular de Parinaud Causada por Sporothrix schenckii. Journal of the Portuguese Society of Dermatology and Venereology, 76(4), 429–433. https://doi.org/10.29021/spdv.76.4.886
Mahajan, V. K. (2014). Sporotrichosis: an overview and therapeutic options. Dermatology research and practice, 2014.
Morris-Jones, R. (2002). Sporotrichosis. Clinical and Experimental Dermatology, 27(6), 427–431. https://doi.org/10.1046/j.1365-2230.2002.01087.x
Neto, A. O. L., Caetano, T. R., Gervasio, N. H. P., & Carneiro, R. C. (2021). Conjunctival and bulbar sporotrichosis as Parinaud’s oculoglandular syndrome acquired by blood inoculation. GMS Ophthalmology Cases, 11, Doc02. DOI: 10.3205/oc000175
Niklitschek, S., Porras, N., González, S., & Romero, W. (2015). Esporotricosis. Medicina Clinica, 145(9), 418. https://doi.org/10.1016/j.medcli.2015.01.027
Orofino-Costa, R., Rodrigues, A. M., de Macedo, P. M., & Bernardes-Engemann, A. R. (2017). Sporotrichosis: An update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics. Anais Brasileiros de Dermatologia, 92(5), 606–620. https://doi.org/10.1590/abd1806-4841.2017279
Paul Yan, P. A. (2015). Parinaud Oculoglandular Syndrome 2015: Review of the Literature and Update on Diagnosis and Management. Journal of Clinical & Experimental Ophthalmology, 06(03). https://doi.org/10.4172/2155-9570.1000443
Ribeiro, C. R., Silva, B. P., Costa, A. D. A. A., Neto, A. B., Vieira, L. A., de Lima, M. A., & de Lima, M. H. C. (2020). Ocular Sporotrichosis. American Journal of Ophthalmology Case Reports, 19, 100865. DOI: 10.1016/j.ajoc.2020.100865
Queiroz-Telles, F., Buccheri, R., & Benard, G. (2019). Sporotrichosis in immunocompromised hosts. Journal of Fungi, 5(1), 1–23. https://doi.org/10.3390/jof5010008
Ramos-e-Silva, M., Vasconcelos, C., Carneiro, S., & Cestari, T. (2007). Sporotrichosis. Clinics in Dermatology, 25(2), 181–187. https://doi.org/10.1016/j.clindermatol.2006.05.006
Shields, M., Sinkar, S., Chan, W. O., & Crompton, J. (2017). Parinaud syndrome: a 25-year (1991–2016) review of 40 consecutive adult cases. Acta Ophthalmologica, 95(8), e792–e793. https://doi.org/10.1111/aos.13283
Yamagata, J. P. M., Rudolph, F. B., Nobre, M. C. L., Nascimento, L. V., Sampaio, F. M. S., Arinelli, A., & Freitas, D. F. (2017). Ocular sporotrichosis: A frequently misdiagnosed cause of granulomatous conjunctivitis in epidemic areas. American journal of ophthalmology case reports, 8, 35-38. DOI: 10.1016/j.ajoc.2017.09.005
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