Treatment satisfaction and quality of life of adolescents with T1DM using continuous subcutaneous insulin infusion

Authors

  • Lígia Lima Escola Superior de Enfermagem do Porto, CINTESIS, Porto, Portugal https://orcid.org/0000-0003-4556-0485
  • Rute Silva Centro Materno-Infantil do Norte, Porto, Portugal
  • Helena Cardoso Instituto de Ciências Biomédicas Abel Salazar, Serviço de Endocrinologia Centro Hospitalar e Universitário do Porto, Portugal
  • Teresa Martins Escola Superior de Enfermagem do Porto, CINTESIS, Porto, Portugal

DOI:

https://doi.org/10.29352/mill0218.25955

Keywords:

type 1 diabetes, adolescents, quality of life, patient satisfaction

Abstract

Introduction: Continuous subcutaneous insulin infusion (CSII) has been prioritised in the metabolic control of type 1 Diabetes Mellitus (T1DM) in children and adolescents.

Objective: To assess the quality of life and treatment satisfaction in adolescents with T1DM using CSII and analyse the role of quality of life in predicting treatment satisfaction among these adolescents.

Methods: The sample comprised 77 adolescents aged 10 to 18, followed-up in two central hospitals in the Northern region of Portugal. The Quality-of-Life questionnaire for treatment with Insulin Infusion Pump – adolescents’ version - and the adapted version for adolescents of treatment satisfaction with Insulin Pump questionnaire were used.

Results: Most adolescents reported a good quality of life, with lower values in the dimensions related to the Impact of Diabetes, Feelings and Mood and Leisure. They were satisfied with the CSII system, recognizing it as convenient, easy to use and guarantying autonomy. A prediction model was tested through multiple linear regression, with the Impact of diabetes, Leisure Time and Feelings and mood explaining 32.7% of the variance of treatment satisfaction.

Conclusion: CSII is a therapeutic option that adolescents with T1DM perceive to promote their quality of life and consider satisfactory, in line with the previous evidence. However, interventions aimed to support these adolescents in managing their disease and treatment should focus on aspects such as self-image and emotional well-being.

References

Alvarenga, C. S., La Banca, R. O., Neris, R. R., de Cássia Sparapani, V., Fuentealba-Torres, M., Cartagena-Ramos, D., … & Nascimento, L. C. (2022). Use of continuous subcutaneous insulin infusion in children and adolescents with type 1 diabetes Mellitus: a systematic mapping review. BMC endocrine disorders, 22(1), 43. https://doi.org/10.1186/s12902- 022-00950-7

Afonso, A., & Nunes, C. (2019). Probabilidades e Estatística. Aplicações e Soluções em SPSS. Editora: Universidade de Évora.

Alsaleh, F., Smith, F., & Taylor, K. (2012). Experiences of children/young people and their parents, using insulin pump therapy for the management of type 1 diabetes: Qualitative review. Journal of Clinical Pharmacy and Therapeutics, 37 (2), 140–47. https://doi.org/10.1111/j.1365-2710.2011.01283.x.

Alsaleh, F. M., Smith, F. J., Thompson, R., Al-Saleh, M. A., & Taylor, K. M. (2014). Insulin pump therapy: impact on the lives of children/young people with diabetes mellitus and their parents. International journal of clinical pharmacy, 36(5), 1023– 1030. https://doi.org/10.1007/s11096-014-9990-1

Apolinário, D., Silva, I., Ribeiro, J., Vilaverde, J., Dores, F. ,… & Cardoso, H. (2010). Construção de questionários para avaliação da qualidade de vida e satisfação com o tratamento com bomba infusora de insulina: Estudo descritivo e contributo para a validação. Revista Portuguesa de Endocrinologia, Diabetes e Metabolismo, 1, 35–57.

Benioudakis, E., Karlafti, E., Kalaitzaki, A., Kaiafa, G., Savopoulos, C., & Didangelos, T. (2021). Technological developments and quality of life in Type 1 Diabetes Mellitus Patients: A review of the modern insulin analogues, continuous glucose monitoring and insulin pump therapy. Current diabetes reviews, 10.2174/1573399818666211103163208. Advance online publication. https://doi.org/10.2174/1573399818666211103163208

Brew-Sam N., Chhabra M., Parkinson A., Hannan K., Brown E., Pedley L., … & Desborough, J. (2021). Experiences of young people and their caregivers of using technology to manage Type 1 Diabetes Mellitus: Systematic literature review and narrative synthesis. JMIR Diabetes, 6(1), e20973. DOI: 10.2196/20973

Cruz, D., Collet, N., & Nóbrega, V. M. (2018). Quality of life related to health of adolescents with dm1: an integrative review. Qualidade de vida relacionada à saúde de adolescentes com dm1- revisão integrativa. Ciência & Saúde Coletiva, 23(3), 973–989. https://doi.org/10.1590/1413-81232018233.08002016

Direção Geral de Saúde (2019). Crianças e jovens com diabetes. Manual de formação para apoio aos profissionais de saúde e de educação. https://www.dgs.pt/documentos-e-publicacoes/criancas-e-jovens-com-diabetes-mellitus-tipo-1-manual-de- formacao-para-apoio-aos-profissionais-de-saude-e-de-educacao-pdf.aspx.

Driscoll, K., J. Raymond, D. Naranjo, & S. Patton (2016). Fear of hypoglycemia in children and adolescents and their parents with Type 1 Diabetes. Current Diabetes Report, 16(8), 77. https://doi.org/10.1007/s11892-016-0762-2.

Haas, J., Persson, M., Hagström Toft, E., Rathsman, B., Brorsson, A. L., & Lindholm Olinder, A. (2020). Treatment satisfaction correlated with glycaemic control and burden of diabetes in Swedish adolescents with type 1 diabetes. Acta paediatrica, 109(3), 573–580. https://doi.org/10.1111/apa.14991

Hussain, T., Akle, M., Nagelkerke, N., & Deeb, A. (2017). Comparative study on treatment satisfaction and health perception in children and adolescents with type 1 diabetes mellitus on multiple daily injection of insulin, insulin pump and sensor- augmented pump therapy. SAGE Open Medicine, 5, 2050312117694938. https://doi.org/10.1177/2050312117694938

Keller, M., Attia, R., Beltrand, J., Djadi-Prat, J., Nguyen-Khoa, T., Jay, J. P., Cahané, M., Choleau, C., & Robert, J. J. (2017). Insulin regimens, diabetes knowledge, quality of life, and HbA1c in children and adolescents with type 1 diabetes. Pediatric Diabetes, 18(5), 340–347. https://doi.org/10.1111/pedi.12397

Korkmaz, Ö., Demir, G., Çetin, H., Mecidov, İ., Atik Altınok, Y., Özen, S., Darcan, Ş., & Gökşen, D. (2018). Effectiveness of continuous subcutaneous insulin infusion pump therapy during five years of treatment on metabolic control in children and adolescents with type 1 diabetes Mellitus. Journal of Clinical Research in Pediatric Endocrinology, 10(2), 147–152. https://doi.org/10.4274/jcrpe.5117

Modzelewski, K., Fantasia, K., & Steenkamp, D. (2019). Reconsidering meaningful outcomes in diabetes mHealth research. US Endocrinology, 15(2),74–6 https://doi.org/10.17925/USE.2019.15.2.74

Lukács, A., Mayer, K., Sasvári, P., & Barkai, L. (2018). Health-related quality of life of adolescents with type 1 diabetes in the context of resilience. Pediatric Diabetes, 19(8), 1481–1486. https://doi.org/10.1111/pedi.12769

Mueller-Godeffroy, E., Vonthein, R., Ludwig-Seibold, C., Heidtmann, B., Boettcher, C., Kramer, M., Hessler, N., Hilgard, D., Lilienthal, E., Ziegler, A., Wagner, V. M., & German Working Group for Pediatric Pump Therapy (agip) (2018). Psychosocial benefits of insulin pump therapy in children with diabetes type 1 and their families: The pumpkin multicenter randomized controlled trial. Pediatric Diabetes, 19(8), 1471–1480. https://doi.org/10.1111/pedi.12777

Observatório da diabetes (2016). Diabetes: Factos e Números Ano 2015. Relatório Anual Do Observatório Nacional de Diabetes. https://www.spd.pt/index.php/notcias-topmenu-19/663-2017-03-16-16-19-17.

Özyazıcıoğlu, N., Avdal, E. Ü., & Sağlam, H. (2017). A determination of the quality of life of children and adolescents with type 1 diabetes and their parents. International Journal of Nursing Sciences, 4(2), 94–98. https://doi.org/10.1016/j.ijnss.2017.01.008

Patterson, C. C., Karuranga, S., Salpea, P., Saeedi, P., Dahlquist, G., Soltesz, G., & Ogle, G. D. (2019). Worldwide estimates of incidence, prevalence and mortality of type 1 diabetes in children and adolescents: Results from the International Diabetes Federation Diabetes Atlas, 9th edition. Diabetes Research and Clinical Practice, 157, 107842. https://doi.org/10.1016/j.diabres.2019.107842

Rosner, B., & Roman-Urrestarazu, A. (2019). Health-related quality of life in paediatric patients with Type 1 diabetes mellitus using insulin infusion systems. A systematic review and meta-analysis. PloS One, 14(6), e0217655. https://doi.org/10.1371/journal.pone.0217655

Rubin, R. R., Peyrot, M., & STAR 3 Study Group (2012). Health-related quality of life and treatment satisfaction in the Sensor- Augmented Pump Therapy for A1C Reduction 3 (STAR 3) trial. Diabetes Technology & Therapeutics, 14(2), 143–151. https://doi.org/10.1089/dia.2011.0162

Al Shaikh, A., Al Zahrani, A. M., Qari, Y. H., AbuAlnasr, A. A., Alhawsawi, W. K., Alshehri, K. A., & AlShaikh, S. A. (2020). Quality of life in children with diabetes treated with insulin pump compared with multiple daily injections in Tertiary Care Center. Clinical medicine insights. Endocrinology and Diabetes, 13, 1179551420959077. https://doi.org/10.1177/1179551420959077

Silva, N., Patraquim, C., Fernandes, V., Costa, F., Marques, O. & Antunes, A. (2017). Avaliação da qualidade de vida das crianças e adolescentes com diabetes Mellitus Tipo 1 e Sistema de Infusão Subcutânea Contínua de insulina. Revista Portuguesa de Endocrinologia, Diabetes e Metabolismo, 12(2), 151–60.

Sousa, I. (2014). Construção de questionários para avaliação da qualidade devVida e satisfação com o tratamento com bomba infusora de insulina em adolescentes: Estudo descritivo e análise psicométrica. Dissertação de mestrado. Instituto de Ciências Biomédicas de Abel Salazar da Universidade do Porto.

Downloads

Published

2022-05-31

How to Cite

Lima, L., Silva, R. ., Cardoso, H. ., & Martins, T. . (2022). Treatment satisfaction and quality of life of adolescents with T1DM using continuous subcutaneous insulin infusion. Millenium - Journal of Education, Technologies, and Health, 2(18), 33–41. https://doi.org/10.29352/mill0218.25955

Issue

Section

Life and Healthcare Sciences