Consensus-based physiotherapy interventions for the treatment of diabetic foot ulcers: a Delphi study
DOI:
https://doi.org/10.29352/mill0220e.39718Keywords:
assistive technologies; Delphi survey; neuropathic ulcer; physiotherapy; therapeutic exerciseAbstract
Introduction: Diabetic foot ulcers are a common complication that occurs in patients with diabetes mellitus. The literature describes the treatment as multidisciplinary and also the benefits of physiotherapy as an adjuvant therapy in the treatment of diabetic foot ulcers.
Objective: To investigate physiotherapeutic interventions for the management of foot ulceration in people with diabetes.
Methods: Exploratory and descriptive study using the Delphi method. The interventions resulted from a systematic review of the literature that was submitted to a panel of experts for analysis. The panel consisted of 12 experts in the field of wound care, and two rounds of analysis were carried out. Quantitative analysis was carried out for the agreement of the answers, and qualitative analysis was used on the experts' comments.
Results: In the first round, the expert’s analysis had consensus between 66.7% to 100% within the answers, and in the second round, it ranged from 85.7% to 100%. Two of the interventions in the first round needed to be adjusted. In the second round, all interventions obtained at least 80% consensus.
Conclusion: Physiotherapy can help as an adjuvant therapy in the treatment of diabetic foot ulcers. The intervention includes therapeutic exercise (active mobilization exercises) and the use of assistive technologies (removable or non-removable offloading devices). Physiotherapeutic interventions are an adjuvant therapy to a specific local treatment of the wound and pressure relief.
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Bus, S. A., Armstrong, D. G., Gooday, C., Jarl, G., Caravaggi, C., Viswanathan, V., & Lazzarini, P. A. (2020). Guidelines on offloading foot ulcers in persons with diabetes (IWGDF 2019 update). Diabetes/Metabolism Research and Reviews, 36(S1), 1–18. https://doi.org/10.1002/dmrr.3274
Eraydin, S., & Avsar, G. (2017). The Effect of Foot Exercises on Wound Healing in Type 2 Diabetic Patients with a Foot Ulcer: A Randomized Control Study. Journal of Wound, Ostomy and Continence Nursing, 45(2), 123–130. https://doi.org/10.1097/WON.0000000000000405
Huang, H., Xin, R., Li, X., Zhang, X., Chen, Z., Zhu, Q., Tai, Z., & Bao, L. (2023). Physical therapy in diabetic foot ulcer: Research progress and clinical application. International Wound Journal, 20(8), 3417–3434. https://doi.org/10.1111/iwj.14196
Khalifa, W. A., Argoon, S. A., & AbdEllah-Alawi, M. H. (2023). Determinants of healing of diabetic foot ulcer comparing two offloading modalities: A randomized prospective study. The Foot, 56. https://doi.org/10.1016/j.foot.2023.102016
Lazzarini, P. A., Jarl, G., Gooday, C., Viswanathan, V., Caravaggi, C. F., Armstrong, D. G., & Bus, S. A. (2020). Effectiveness of offloading interventions to heal foot ulcers in persons with diabetes: a systematic review. Diabetes/Metabolism Research and Reviews, 36(S1). https://doi.org/10.1002/dmrr.3275
Lindberg, K., Møller, B. S., Kirketerp-Møller, K., & Kristensen, M. T. (2018). An exercise program for people with severe peripheral neuropathy and diabetic foot ulcers–a case series on feasibility and safety. Disability and Rehabilitation, 42(2), 183–189. https://doi.org/10.1080/09638288.2018.1494212
Ling, E., Lepow, B., Zhou, H., Enriquez, A., Mullen, A., & Najafi, B. (2020). The impact of diabetic foot ulcers and unilateral offloading footwear on gait in people with diabetes. Clinical Biomechanics, 73(September 2019), 157–161. https://doi.org/10.1016/j.clinbiomech.2020.01.014
Medeiros, S., Rodrigues, A., & Costa, R. (2023). Physiotherapeutic interventions in the treatment of patients with diabetic foot ulcers: a systematic literature review. Physiotherapy, 118, 79–87. https://doi.org/10.1016/j.physio.2022.09.006
Medeiros, S., Rodrigues, A., & Costa, R. (2024). Physiotherapy Intervention in the Treatment of Venous Ulcers: Results from a Delphi Panel. Journal of Vascular Diseases, 3(4), 508–519. https://doi.org/10.3390/jvd3040038
Musuuza, J., Sutherland, B. L., Kurter, S., Balasubramanian, P., Bartels, C. M., & Brennan, M. B. (2020). A systematic review of multidisciplinary teams to reduce major amputations for patients with diabetic foot ulcers. Journal of Vascular Surgery, 71(4), 1433-1446.e3. https://doi.org/10.1016/j.jvs.2019.08.244
Najafi, B., Grewal, G. S., Bharara, M., Menzies, R., Talal, T. K., & Armstrong, D. G. (2016). Can ’ t Stand the Pressure : The Association Between Unprotected Standing , Walking , and Wound Healing in People With Diabetes. https://doi.org/10.1177/1932296816662959
Park, C., Mishra, R., Vigano, D., Macagno, M., Rossotti, S., D’Huyvetter, K., Garcia, J., Armstrong, D. G., & Najafi, B. (2023). Smart Offloading Boot System for Remote Patient Monitoring: Toward Adherence Reinforcement and Proper Physical Activity Prescription for Diabetic Foot Ulcer Patients. Journal of Diabetes Science and Technology, 17(1), 42–51. https://doi.org/10.1177/19322968211070850
Perez-Favila, A., Martinez-Fierro, M. L., Rodriguez-Lazalde, J. G., Cid-Baez, M. A., Zamudio-Osuna, M. D. J., Martinez-Blanco, M. D. R., Mollinedo-Montaño, F. E., Rodriguez-Sanchez, I. P., Castañeda-Miranda, R., & Garza-Veloz, I. (2019). Current therapeutic strategies in diabetic foot ulcers. Medicina (Lithuania), 55(11), 1–21. https://doi.org/10.3390/medicina55110714
Qiu, S., Cai, X., Yin, H., Sun, Z., Zügel, M., Steinacker, J. M., & Schumann, U. (2018). Exercise training and endothelial function in patients with type 2 diabetes: A meta-analysis. Cardiovascular Diabetology, 17(1), 1–12. https://doi.org/10.1186/s12933-018-0711-2
Rai, V., Moellmer, R., & Agrawal, D. K. (2023). Role of fibroblast plasticity and heterogeneity in modulating angiogenesis and healing in the diabetic foot ulcer. Molecular Biology Reports, 50(2), 1913–1929. https://doi.org/10.1007/s11033-022-08107-4
Rodrigues, A. M., Ferreira, P. L., Lourenço, C., Alves, P. J. P., Marques, J. M. N. D., & de Sá, L. O. (2022). Chronic wound assessment: Cultural and linguistic adaptation for European Portuguese of RESVECH-2 scale. Journal of Tissue Viability, 31(4), 783–789. https://doi.org/10.1016/j.jtv.2022.07.004
Schaper, N. C., van Netten, J. J., Apelqvist, J., Bus, S. A., Fitridge, R., Game, F., Monteiro-Soares, M., & Senneville, E. (2024). Practical guidelines on the prevention and management of diabetes-related foot disease (IWGDF 2023 update). Diabetes/Metabolism Research and Reviews, 40(3). https://doi.org/10.1002/dmrr.3657
Su, N., Xu, T., Li, X., Zheng, H., Wu, B., Zhang, S., Zhou, Y., Du, L., & Zhao, Y. (2022). Heparin and Related Substances for Treating Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis. Frontiers in Endocrinology, 13(February), 1–11. https://doi.org/10.3389/fendo.2022.749368
Suryani, M., Samekto, W., Heri-Nugroho, Susanto, H., & Dwiantoro, L. (2021). Effect of foot-ankle flexibility and resistance exercise in the secondary prevention of plantar foot diabetic ulcer. Journal of Diabetes and Its Complications, 35(9), 107968. https://doi.org/10.1016/j.jdiacomp.2021.107968
Tran, M. M., & Haley, M. N. (2021). Does exercise improve healing of diabetic foot ulcers? A systematic review. Journal of Foot and Ankle Research, 14(1), 1–9. https://doi.org/10.1186/s13047-021-00456-w
Vangaveti, V. N., Jhamb, S., Goodall, J., Bulbrook, J., Biros, E., & Malabu, U. H. (2023). Extracorporeal Shockwave Therapy (ESWT) in the Management of Diabetic Foot Ulcer: A Prospective Randomized Clinical Trial. The Journal of Foot and Ankle Surgery, 62(5), 845–849. https://doi.org/10.1053/j.jfas.2023.04.013
Wennberg, L., Widgren, S., Axelsson, R., Gerok-Andersson, K., & Åkerlund, B. (2019). Multidisciplinary diabetic foot care in Sweden – A national survey. Diabetes Research and Clinical Practice, 149, 126–131. https://doi.org/10.1016/j.diabres.2019.02.003
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