Ewing's sarcoma in the 5th rib
case report
DOI:
https://doi.org/10.29352/mill0219.28093Keywords:
sarcoma, Ewing, chest pain, dyspnea, ribsAbstract
Development - Case Report: A 39-year-old woman consulted her general practitioner with complaints of chest pain with 2 weeks of evolution, which presented itself after physical exercise, and was therefore treated as muscle straining. She felt localized chest discomfort for 3 months, occasionally taking analgesics. She once again visited the health center due to increased pain. The pain was more severe in decubitus position and at night, associated with awakenings and dyspnea. This motivated the physician to perform an X-ray, which identified a 6.5 cm mass in the 5th costal arch. A biopsy was performed at a hospital and Ewing's sarcoma was diagnosed. After diagnostic examination (CT scan and body Scintigraphy) and in the absence of metastases, the patient underwent chemotherapy and total costectomy. She is currently undergoing rehabilitation, with follow-ups at the cancer center and primary health care.
Conclusion: Nonspecific symptomatology can lead to a delay in the diagnosis and treatment of Ewing’s sarcoma. The presentation of this case aims to alert for the existence of this pathology, and the importance of both anamnesis and warning signs during clinical evaluation, thus contributing to an early prognosis and treatment. The prognosis of Ewing’s sarcoma fundamentally depends on whether the disease is localized or metastasized. The therapeutic evolution has increased survival chances, which implies an adequate follow-up of relapses and the after-effects of treatments.
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Biermann, J. S., Chow, W., Reed, D. R., Lucas, D., Adkins, D. R., Agulnik, M., Benjamin, R. S., Brigman, B., Budd, G. T., Curry, W. T., Didwania, A., Fabbri, N., Hornicek, F. J., Kuechle, J. B., Lindskog, D., Mayerson, J., McGarry, S. V., Million, L., Morris, C. D., Movva, S., … Scavone, J. L. (2017). NCCN Guidelines Insights: Bone Cancer, Version 2.2017. Journal of the National Comprehensive Cancer Network : JNCCN, 15(2), 155–167. https://doi.org/10.6004/jnccn.2017.0017
Cotterill, S. J., Ahrens, S., Paulussen, M., Jürgens, H. F., Voûte, P. A., Gadner, H., & Craft, A. W. (2000). Prognostic factors in Ewing's tumor of bone: analysis of 975 patients from the European Intergroup Cooperative Ewing's Sarcoma Study Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 18(17), 3108–3114. https://doi.org/10.1200/JCO.2000.18.17.3108
Ebrahimpour, A., Chehrassan, M., Sadighi, M., Azizmohammad Looha, M., Karimi, A., Akbari, A., Raeisi, A., & Akbari, M. E. (2020). The Survival and Incidence Rate of Ewing Sarcoma; a National Population-based Study in Iran (2008-2015). The archives of bone and joint surgery, 8(3), 391–399. https://doi.org/10.22038/abjs.2020.44095.2206
Errani, C., Tsukamoto, S., & Mavrogenis, A. F. (2020). Imaging Analyses of Bone Tumors. JBJS reviews, 8(3), e0077. https://doi.org/10.2106/JBJS.RVW.19.00077
-Grünewald, T.G.P., Cidre-Aranaz, F., Surdez, D. et al. (2018). Ewing sarcoma. Nat Rev Dis Primers 4, 5. https://doi.org/10.1038/s41572-018-0003-x
Ferrari, S., Bertoni, F., Mercuri, M., Sottili, S., Versari, M., & Bacci, G. (2001). Ewing's sarcoma of bone: relation between clinical characteristics and staging. Oncology reports, 8(3), 553–556. https://doi.org/10.3892/or.8.3.553
Friedman, D. N., Chastain, K., Chou, J. F., Moskowitz, C. S., Adsuar, R., Wexler, L. H., Chou, A. J., DeRosa, A., Candela, J., Magnan, H., Pun, S., Kahan, T., Wolden, S. L., Meyers, P. A., & Oeffinger, K. C. (2017). Morbidity and mortality after treatment of Ewing sarcoma: A single-institution experience. Pediatric blood & cancer, 64(11), 10.1002/pbc.26562. https://doi.org/10.1002/pbc.26562
Gaspar, N., Hawkins, D. S., Dirksen, U., Lewis, I. J., Ferrari, S., Le Deley, M. C., Kovar, H., Grimer, R., Whelan, J., Claude, L., Delattre, O., Paulussen, M., Picci, P., Sundby Hall, K., van den Berg, H., Ladenstein, R., Michon, J., Hjorth, L., Judson, I., Luksch, R., … Oberlin, O. (2015). Ewing Sarcoma: Current Management and Future Approaches Through Collaboration. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 33(27), 3036–3046. https://doi.org/10.1200/JCO.2014.59.5256
Shamberger, R. C., Laquaglia, M. P., Krailo, M. D., Miser, J. S., Pritchard, D. J., Gebhardt, M. C., Healey, J. H., Tarbell, N. J., Fryer, C. J., Meyers, P. A., & Grier, H. E. (2000). Ewing sarcoma of the rib: results of an intergroup study with analysis of outcome by timing of resection. The Journal of thoracic and cardiovascular surgery, 119(6), 1154–1161. https://doi.org/10.1067/mtc.2000.106330
Widhe, B., Widhe, T., & Bauer, H. C. (2007). Ewing sarcoma of the rib--initial symptoms and clinical features: tumor missed at the first visit in 21 of 26 patients. Acta orthopaedica, 78(6), 840–844. https://doi.org/10.1080/17453670710014644
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