Estudos preliminares de Adsorventes Lenhocelulósicos para a Remoção de Cefalosporinas
DOI:
https://doi.org/10.29352/mill0216e.40973Keywords:
adsorption; kinetics models; lignocellulosic materials; cephalosporin; Acacia dealbataAbstract
Introduction: Acacia dealbata was explored as a biosorbent to remove cephalosporin from aqueous solutions. This study intends to demonstrate the feasibility of using lignocellulosic low-cost materials in the removal of pollutants, valorizing waste from other industries, and reducing the associated environmental impact.
Objective: The aim of this study was to evaluate the capacity of acacia residues to adsorb cephalosporin, analyze its adsorption potential, and examine the kinetic models involved in order to explore its use in water treatment.
Methods: This review was conducted using a systematic approach to identify, analyze, and synthesize the relevant literature on the presence and impact of cephalosporin antibiotics in aquatic environments. In parallel, adsorption tests were performed using cephalosporin solutions with a concentration of 15 mg L⁻¹, varying the stirring time between 10 and 120 minutes. The adsorption kinetics were evaluated based on the pseudo-first order, pseudo-second order, Elovich, and intraparticle diffusion models. The adsorption was analyzed by UV-Vis spectrometry, where a characteristic absorption peak at 240 nm was identified.
Results: The results indicated that the pseudo-first order model presented the highest coefficient of determination (R² = 0.991), suggesting that the predominant mechanism is physical adsorption. This analysis confirmed the ability of acacia to adsorb cephalosporins, evidencing its potential as a biosorbent.
Conclusion: This study highlights the relevance of biosorbents, such as Acacia dealbata, in the treatment of pollutants from the pharmaceutical industry. The use of sustainable materials offers a promising solution for water treatment, paving the way for future applications in the field of biosorption.
Downloads
References
Abdullah, M., Iqbal, J., Ur Rehman, M. S., Khalid, U., Mateen, F., Arshad, S. N., Al-Sehemi, A. G., Algarni, H., Al-Hartomy, O. A., & Fazal, T. (2023). Removal of ceftriaxone sodium antibiotic from pharmaceutical wastewater using an activated carbon-based TiO2 composite: Adsorption and photocatalytic degradation evaluation. Chemosphere, 317, 137834. https://doi.org/10.1016/j.chemosphere.2023.137834
Abramović, B. F., Uzelac, M. M., Armaković, S. J., Gašić, U., Četojević-Simin, D. D., & Armaković, S. (2021). Experimental and computational study of hydrolysis and photolysis of antibiotic ceftriaxone: Degradation kinetics, pathways, and toxicity. Science of the Total Environment, 768, 144991. https://doi.org/10.1016/j.scitotenv.2021.144991
Akhtar, J., Amin, N. A. S., & Shahzad, K. (2016). A review on removal of pharmaceuticals from water by adsorption. Desalination and Water Treatment, 57, 12842–12860. https://doi.org/10.1080/19443994.2015.1051121
Ali, I., ALOthman, Z. A., & Mbianda, X. Y. (2023). Preparation and characterization of nanoporous carbon for removal of amoxicillin antibiotic from water: Modelling, kinetics and thermodynamic studies. Inorganic Chemistry Communications, 155, 111006. https://doi.org/10.1016/j.inoche.2023.111006
Baccar, R., Sarrà, M., Bouzid, J., Feki, M., & Blánquez, P. (2012). Removal of pharmaceutical compounds by activated carbon prepared from agricultural by-product. Chemical Engineering Journal, 211–212, 310–317. https://doi.org/10.1016/j.cej.2012.09.099
Caique Alves, T., Cabrera-Codony, A., Barceló, D., Rodriguez-Mozaz, S., Pinheiro, A., & Gonzalez-Olmos, R. (2018). Influencing factors on the removal of pharmaceuticals from water with micro-grain activated carbon. Water Research, 144, 402–412. https://doi.org/10.1016/j.watres.2018.07.037
Carabineiro, S. A. C., Thavorn-Amornsri, T., Pereira, M. F. R., & Figueiredo, J. L. (2011). Adsorption of ciprofloxacin on surface-modified carbon materials. Water Research, 45, 4583–4591. https://doi.org/10.1016/j.watres.2011.06.008
Chernomorova, M. A., Myakinina, M. S., Zhinzhilo, V. A., & Uflyand, I. E. (2023). Analytical determination of cephalosporin antibiotics using coordination polymer based on cobalt terephthalate as a sorbent. Polymers, 15(3), 548. https://doi.org/10.3390/polym15030548
Correia, A., & Marcano, L. (2015). Presence and elimination of pharmaceutical compounds in wastewater treatment plants: Worldwide review and national perspective. Boletín de Malariología y Salud Ambiental, 55, 1–18. https://ve.scielo.org/pdf/bmsa/v55n1/art01.pdf
Cruz-Lopes, L., Macena, M., Esteves, B., & Santos-Vieira, I. (2022). Lignocellulosic materials used as biosorbents for the capture of nickel (II) in aqueous solution. Applied Sciences, 12, 933. https://doi.org/10.3390/app12020933
Da Trindade, M. T., & Salgado, H. R. N. (2018). A critical review of analytical methods for determination of ceftriaxone sodium. Critical Reviews in Analytical Chemistry, 48, 95–101. https://doi.org/10.1080/10408347.2017.1398063
Das, N., Madhavan, J., Selvi, A., & Das, D. (2019). An overview of cephalosporin antibiotics as emerging contaminants: A serious environmental concern. 3 Biotech, 9. https://doi.org/10.1007/s13205-019-1766-9
Gholamiyan, S., Hamzehloo, M., & Farrokhnia, A. (2020). RSM optimized adsorptive removal of erythromycin using magnetic activated carbon: Adsorption isotherm, kinetic modeling and thermodynamic studies. Sustainable Chemistry and Pharmacy, 17, 100309. https://doi.org/10.1016/j.scp.2020.100309
Gracia-Lor, E., Sancho, J. V., Serrano, R., & Hernandez, F. (2012). Occurrence and removal of pharmaceuticals in wastewater treatment plants at the Spanish Mediterranean area of Valencia. Chemosphere, 87, 453–462. https://doi.org/10.1016/j.chemosphere.2011.12.025
Ho, Y. S., & McKay, G. (1998). A comparison of chemisorption kinetic models applied to pollutant removal on various sorbents. Process Safety and Environmental Protection, 76, 332–340. https://doi.org/10.1205/095758298529696
Jelic, A., Gros, M., Ginebreda, A., Cespedes-Sanchez, R., Ventura, F., Petrovic, M., & Barceló, D. (2011). Occurrence, partition and removal of pharmaceuticals in sewage water and sludge during wastewater treatment. Water Research, 45, 1165–1176. https://doi.org/10.1016/j.watres.2010.11.010
Khan, A. H., Khan, N. A., Zubair, M., Shaida, M. A., Manzar, M. S., Abutaleb, A., Naushad, M., & Iqbal, J. (2022). Sustainable green nanoadsorbents for remediation of pharmaceuticals from water and wastewater: A critical review. Environmental Research, 204, 112243. https://doi.org/10.1016/j.envres.2021.112243
Khasawneh, O. F. S., & Palaniandy, P. (2021). Occurrence and removal of pharmaceuticals in wastewater treatment plants. Process Safety and Environmental Protection, 150, 532–556. https://doi.org/10.1016/j.psep.2021.04.045
Kowalska, K., Felis, E., Gnida, A., Luczkiewicz, A., Ziembinska-Buczynska, A., & Surmacz-Gorska, J. (2020). Removal of antibacterial drugs in urban wastewater treatment plants. Desalination and Water Treatment, 199, 152–158. https://doi.org/10.5004/dwt.2020.25463
Lach, J. (2024). Kinetics, statics and thermodynamics of ampicillin adsorption on microporous carbon sorbents. Desalination and Water Treatment, 317, 100144. https://doi.org/10.1016/j.dwt.2024.100144
Lagergren, S. (1898). About the theory of so-called adsorption of soluble substances. https://doi.org/10.4236/jwarp.2016.813095
Li, B., & Zhang, T. (2013). Different removal behaviours of multiple trace antibiotics in municipal wastewater chlorination. Water Research, 47, 2970–2982. https://doi.org/10.1016/j.watres.2013.03.001
Macena, M. W. (2021). Análise do potencial de adsorção de iões metálicos em solução aquosa por resíduos lenhocelulósicos. https://doi.org/10.13140/RG.2.2.11381.45283
Mardani, G., Ahankoub, M., Alikhani Faradonbeh, M., Raeisi Shahraki, H., & Fadaei, A. (2023). Biodegradation of ceftriaxone in soil using dioxygenase-producing genetically engineered Pseudomonas putida. Bioremediation Journal, 27, 400–411. https://doi.org/10.1080/10889868.2022.2057412
Mohammadi Nezhad, A., Talaiekhozani, A., Mojiri, A., Sonne, C., Cho, J., Rezania, S., & Vasseghian, Y. (2023). Photocatalytic removal of ceftriaxone from wastewater using TiO2/MgO under ultraviolet radiation. Environmental Research, 229, 115915. https://doi.org/10.1016/j.envres.2023.115915
Naeini, A., & Moradi, S. (2023). Adsorption method for removal of pharmaceuticals from wastewater: Review. Iranian Journal of Materials Science and Engineering, 20. https://doi.org/10.22068/ijmse.3385
National Center for Biotechnology Information. (2025, February 4). Ceftriaxone sodium. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/71307090
Pereira, J. M., Calisto, V., & Santos, S. M. (2019). Computational optimization of bioadsorbents for the removal of pharmaceuticals from water. Journal of Molecular Liquids, 279, 669–676. https://doi.org/10.1016/j.molliq.2019.01.167
Phan, H. N. Q., Leu, H.-J., & Nguyen, V. N. D. (2024). Enhancing pharmaceutical wastewater treatment: Ozone-assisted electrooxidation and precision optimization via response surface methodology. Journal of Water Process Engineering, 58, 104782. https://doi.org/10.1016/j.jwpe.2024.104782
Puddoo, H., Nithyanandam, R., & Nguyenhuynh, T. (2017). Degradation of the antibiotic ceftriaxone by Fenton oxidation process and compound analysis. Journal of Physical Science, 28, 95–114. https://doi.org/10.21315/jps2017.28.3.7
Ribeiro, A. R., Sures, B., & Schmidt, T. C. (2018). Cephalosporin antibiotics in the aquatic environment: A critical review of occurrence, fate, ecotoxicity and removal technologies. Environmental Pollution, 241, 1153–1166. https://doi.org/10.1016/j.envpol.2018.06.040
Rivera-Utrilla, J., Sánchez-Polo, M., Ferro-García, M. Á., Prados-Joya, G., & Ocampo-Pérez, R. (2013). Pharmaceuticals as emerging contaminants and their removal from water: A review. Chemosphere, 93, 1268–1287. https://doi.org/10.1016/j.chemosphere.2013.07.059
Roginsky, S., & Zeldovich, Y. B. (1934). The catalytic oxidation of carbon monoxide on manganese dioxide. Acta Physicochimica U.R.S.S, 1, 2019. https://doi.org/10.1021/ja01417a002
Samal, K., Mahapatra, S., & Ali, M. H. (2022). Pharmaceutical wastewater as emerging contaminants (EC): Treatment technologies, impact on environment and human health. Energy Nexus, 6, 100076. https://doi.org/10.1016/j.nexus.2022.100076
Sen, U., Esteves, B., Aguiar, T., & Pereira, H. (2023). Removal of antibiotics by biochars: A critical review. Applied Sciences, 13(21), 11963. https://doi.org/10.3390/app132111963
Sophia, A. C., Lima, E. C., Allaudeen, N., & Rajan, S. (2016). Application of graphene-based materials for adsorption of pharmaceutical traces from water and wastewater: A review. Desalination and Water Treatment, 57, 27573–27586. https://doi.org/10.1080/19443994.2016.1172989
Sundararaman, S., & Saravanane, R. (2010). Effect of loading rate and HRT on the removal of cephalosporin and their intermediates during the operation of a membrane bioreactor treating pharmaceutical wastewater. Water Science & Technology, 61(7), 1907–1914. https://doi.org/10.2166/wst.2010.881
Tiwari, B., Sellamuthu, B., Ouarda, Y., Drogui, P., Tyagi, R. D., & Buelna, G. (2017). Review on fate and mechanism of removal of pharmaceutical pollutants from wastewater using biological approach. Bioresource Technology, 224, 1–12. https://doi.org/10.1016/j.biortech.2016.11.042
Tuc Dinh, Q., Alliot, F., Moreau-Guigon, E., Eurin, J., Chevreuil, M., & Labadie, P. (2011). Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC–MS/MS. Talanta, 85(3), 1238–1245. https://doi.org/10.1016/j.talanta.2011.05.013
Van Eck, N., & Waltman, L. (2010). Software survey: VOSviewer, a computer program for bibliometric mapping. Scientometrics, 84(3), 523–538. https://doi.org/10.1007/s11192-009-0146-3
Wang, B., Li, H., Liu, T., & Guo, J. (2021). Enhanced removal of cephalexin and sulfadiazine in nitrifying membrane-aerated biofilm reactors. Chemosphere, 263, 128224. https://doi.org/10.1016/j.chemosphere.2020.128224
Wang, X. H., & Lin, A. Y. C. (2012). Phototransformation of cephalosporin antibiotics in an aqueous environment results in higher toxicity. Environmental Science & Technology, 46(22), 12417–12426. https://doi.org/10.1021/es301929e
Watkinson, A. J., Murby, E. J., Kolpin, D. W., & Costanzo, S. D. (2009). The occurrence of antibiotics in an urban watershed: From wastewater to drinking water. Science of The Total Environment, 407(8), 2711–2723. https://doi.org/10.1016/j.scitotenv.2008.11.059
Weber, W. J., & Morris, J. C. (1963). Kinetics of adsorption on carbon from solution. Journal of the Sanitary Engineering Division, 89(2), 31–59. https://doi.org/10.1061/JSEDAI.0000430
Yeo, J. Y. J., Aqsha, A., Ismadji, S., & Sunarso, J. (2024). Adsorption kinetics of amoxicillin, ampicillin, and doripenem on organobentonite. AIP Conference Proceedings, 3073(1). https://doi.org/10.1063/5.0123456 (Verifique o DOI correto)
Zhang, S., Liu, C., Yuan, Y., Fan, M., Zhang, D., Wang, D., & Xu, Y. (2020). Selective, highly efficient extraction of Cr(III), Pb(II) and Fe(III) from complex water environment with a tea residue-derived porous gel adsorbent. Bioresource Technology, 311, 123520. https://doi.org/10.1016/j.biortech.2020.123520
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Millenium - Journal of Education, Technologies, and Health

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who submit proposals for this journal agree to the following terms:
a) Articles are published under the Licença Creative Commons (CC BY 4.0), in full open-access, without any cost or fees of any kind to the author or the reader;
b) The authors retain copyright and grant the journal right of first publication, allowing the free sharing of work, provided it is correctly attributed the authorship and initial publication in this journal;
c) The authors are permitted to take on additional contracts separately for non-exclusive distribution of the version of the work published in this journal (eg, post it to an institutional repository or as a book), with an acknowledgment of its initial publication in this journal;
d) Authors are permitted and encouraged to publish and distribute their work online (eg, in institutional repositories or on their website) as it can lead to productive exchanges, as well as increase the impact and citation of published work
Documents required for submission
Article template (Editable format)